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Cancer and inflammation: the potential for prevention. Dr Yuzo Endo, MD, PhD.CAM. New Research proves Endo was right about inflammation.

Cancer and inflammation: the potential for prevention. Dr Yuzo Endo, MD, PhD.CAM. New Research proves Endo was right about inflammation.

Cancer and inflammation: the potential for prevention.

  Cancer and inflammation: the potential for prevention

Biobran – Can this supplement help fight cancer?

Biobran – Can this supplement help fight cancer?

One Sizable Step for Immunology, One Giant Leap for Cancer Patients

One Sizable Step for Immunology, One Giant Leap for Cancer Patientsby Mamdooh Ghoneum Ph.D.(This article originally appeared in Pharmacy Business and The Townsend Letter for Doctors and Patients in 2001. It has been slightly updated in the New Age version.)


From Bench to Bedside: The Growing use of Arabinoxylan Rice Bran (MGN-3 /Biobran) in Cancer Immunotherapy

Arabinoxylan rice bran (MGN-3/Biobran) enhances natural killer cell — mediated cytotoxicity against neuroblastoma in vitro and in vivo

MGN-3/BIOBRAN Enhances Generation of Cytotoxic CD8+ T Cells Via Upregulation of DEC-205 Expression on Dendritic Cells

Modified Arabinoxylan from Rice Bran, MGN-3/Biobran, Sensitizes Metastatic Breast Cancer Cells to Paclitaxel In Vitro

Modified Arabinoxylan Rice Bran (MGN-3/Biobran) Enhances Yeast-induced Apoptosis in Human Breast Cancer Cells In Vitro

Case Reports of Cancer Patients with Hepatic Metastases Treated by Standardized Plant Immunomodulatory Preparations

Biobran MGN-3: Effect of reducing side effects of chemotherapy in breast cancer patients

MGN-3 arabinoxylan rice bran modulates innate immunity in multiple myeloma patients

Synergistic Role of Arabinoxylan Rice Bran (MGN-3/Biobran) in S. cerevisiae-induced Apoptosis of Monolayer Breast Cancer MCF-7 Cells peer-reviewed

Metastatic Hemangiopericytoma of the Skin Treated with Wide Local Excision and MGN-3

Chemopreventive Properties of Dietary Rice Bran: Current Status and Future Prospects

Apoptosis of Breast Cancer MCF-7 Cells In Vitro is Induced Specifically by Yeast and Not by Fungal Myceli

Yeast Therapy For the Treatment of Cancer and its Enhancement by MGN-3/Biobran, an Arabinoxylan Rice Bran

Synergistic apoptotic effect of Arabinoxylan rice bran (MGN-3/Biobran) and Curcumin (Turmeric) on human multiple myeloma cell line U266 in vitro

In Vivo Tumor Inhibitory Effects of Nutritional Rice Bran Supplement MGN-3/Biobran on Ehrlich Carcinoma-Bearing Mice

Activation of Human Monocyte-Derived Dendritic Cells In Vitro by the Biological Response Modifier Arabinoxylan Rice Bran (MGN-3/Biobran)

MGN-3/Biobran, modified arabinoxylan from rice bran, sensitizes human breast cancer cells to chemotherapeutic agent, daunorubicin

Modulation of the anticancer immunity by natural agents: inhibition of T regulatory lymphocyte generation by arabinoxylan in patients with locally limited or metastatic solid tumors

Arabinoxylan Rice Bran (MGN-3) Enhances the Effects of Interventional Therapies for the Treatment of Hepatocellular Carcinoma: A Three-year Randomized Clinical Trial

Epigenetics and Immunosenescence Reversal: An Evidence-Based Longevity Paradigm

Evidence-Based Review of BioBran/ MGN-3 Arabinoxylan Compound as a Complementary Therapy for Conventional Cancer Treatment

Biobran/MGN-3, an arabinoxylan rice bran, enhances NK cell activity in geriatric subjects: A randomized, double-blind, placebo-controlled clinical trial

Modified rice bran hemicellulose inhibits vascular endothelial growth factor-induced angiogenesis in vitro via VEGFR2 and its downstream signaling pathways

Controlled pilot study for cancer patients suffering from chronic fatigue syndrome due to chemotherapy treated with BioBran (MGN-3- Arabinoxylane) and targeted radiofrequency heat therapy

Can a standardized plant immunomodulator (rice bran arabinoxylan concentrate/MGN-3) increase the effects of MEK and BRAF inhibitors with clinical benefit? Case report of a patient with carcinoma in biliary duct

Enhancement of human natural killer cell activity by modified arabinoxylan from rice bran (MGN-3)

NK Immunorestoration of Cancer Patients by MGN-3, A Modified Arabinoxylan Rice Bran (Study of 32 Patients Followed for up to 4 Years)

Modified arabinoxylan rice bran (MGN-3/Biobran) sensitizes human T cell leukemia cells to death receptor (CD95)-inducted apoptosis

The Life Prolongation and QOL Improvement Effect of Rice Bran Arabinoxylan Derivative (MGN-3, BioBran) for Progressive Cancer

The Clinical Significance of BioBran in the Immunotherapy for Cancer

One Case of a Patient with Umbilical Metastasis of Recurrent Cancer (Sister Mary Joseph's Nodule, SMJN) Who has Survived for a Long Time under Immunomodulatory Supplement Therapy

Induction of apoptosis in breast cancer cells by Saccharomyces cerevisiae, the baker's yeast, in vitro

Effect of Long-term Administration of Immunomodulatory Food on Cancer Patients Cmpleting Conventional Treatments

Home Products Research Distributors Contact A Case Where an Immunomodulatory Food was Effective in Conservative Therapy for Progressive Terminal Pancreatic Cancer

Modified Rice Bran Beneficial for Weight Loss of Mice as a Major and Acute Adverse Effect of Cisplatin

Arabinoxylan rice bran (MGN-3/Biobran) enhances radiotherapy in animals bearing Ehrlich ascites carcinoma

Chemopreventive role of arabinoxylan rice bran, MGN-3/Biobran, on liver carcinogenesis in rats

The Immunomodulating Effects of Arabinoxylan Rice Bran (Lentin) on Hematologic Profile, Nutritional Status and Quality of Life among Head and Neck Carcinoma Patients Undergoing Radiation Therapy: A Double Blind Randomized Control Trial

Clinical Cancer Strategy (Clinical Review)


Would Biobran be beneficial for X, Y or Z disease?

Generally, anyone with a disease that involves a lowering of the immune system as a symptom is likely to receive some benefit from Biobran supplementation, although once again it should be stressed that Biobran is NOT a treatment in itself, but a useful supplement to take alongside treatment. Genera

How much Biobran MGN-3 should I take?

As a general rule, higher doses of Biobran tend to get to the optimum immune level or normalization point much more quickly than lower dosages and so are recommended for more serious conditions where speed of recovery is important.   Dosages vary from 500mg a day (half a sachet or 2 tablets) right


This is an absolute con!

This was the knee-jerk response of an oncologist at a leading UK cancer hospital to a patient who asked him to give a professional opinion on Biobran MGN-3. The oncologist in question examined none of the research and stated that he was going to complain to immunologist Professor Ghoneum. Strangely,

My oncologist, who is very knowledgeable and senior in his specialist area, does not see how this could work.

Oncologists are doctors who specialize in cancer treatment. They are not immunologists – scientists who study the immune system. We were recently in contact with a highly credentialed and experienced immunologist who explained to us how little many oncologists know about immunology, and how it gener

Immune system strength and more specifically NK-cell activity is not particularly relevant to cancer survival.

This is contradicted by clinical research, which clearly shows that a strong immune system does have impact on cancer survival. Anyone who takes this view is ignorant of the research out there. Few other beliefs have done more damage to public health than this one, and it has given rise to orthodox

Biobran MGN-3 is ridiculously expensive and is a way for unethical companies to fleece desperate people.

Biobran is expensive. It is made by a pharmaceutical company in Japan using state-of-the-art equipment and it has and continues to be put through many expensive tests and trials, most of which have to be ultimately paid for by the consumer. For the same reasons, drugs produced by the pharmaceutical

Companies promoting this product state that research has shown that people taking [Biobran] MGN-3 have an increased number of natural killer (NK) cells in their blood. This does not prove it can stop a cancer growing.

This is a quote on Biobran MGN-3 from the leading UK cancer charity website Cancer Research UK. It clearly indicates that whoever wrote it did not look very carefully at the research: Biobran does increase the number of NK-cells, but more importantly, it increases their activity. The statement that

…the immune system can recognise cancer cells as abnormal and kill them. Unfortunately, this is not enough to get rid of cancer altogether.

This is another unscientific statement from the same cancer charity. Stating that "this is not enough to get rid of cancer altogether" applies to ANY treatment, orthodox or otherwise, that does not have a 100% success rate measured in terms of survival after a 5 year period, and it merely emphasizes

Only well designed clinical trials can find out if people with cancer who take MGN-3 do better than people who don't. We are not aware of any trials looking into this.

The phrase "well-designed" is deliberately nebulous here because the gold standard for any medical trial is for it to be double-blind placebo controlled, something that most chemotherapeutic agents have NOT been through because of ethical considerations (withholding treatment from a control group in


Prof. Rupert Handgretinger lectures on how to harness the immune system to fight cancer.

Prof. Rupert Handgretinger lectures on how to harness the immune system to fight cancer. 


CANCERactive is the leading holistic cancer information charity that has some great information on the best ways to survive cancer.

They also have a lot of interesting information on their site for those with cancer.

Yes to Life is charity that promotes an integrative approach to cancer care, sellecting those therapies that really work.

Doctor Media

The Important role of the Natural Killer (NK) cells

Prof. Rupert Handgretinger lectures on how to harness the immune system to fight cancer.

Prof. Jurasunas - New Modern Way to Approach Cancer

Presentation from conference in Kraków 2017

Study for cancer patients suffering from chronic fatigue syndrome

Prof. Dr. Hegyi Gabriella MD, PhD, President of Hungarian Biophysical Association for Doctors, Hungary - Biophysical Association for Doctors Controlled pilot study for cancer patients suffering from chronic fatigue syndrome due to chemotherapy treated with BioBran (MGN-3- Arabinoxylan) and Targeted


Natural Killer Cells

Natural Killer Cells are type of white blood cell and a part of innate immune system. NK cells are specialized to kill certain types of target cells, especially host cells that have become infected with virus and host cells that have become cancerous.

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