Controlled pilot study for cancer patients suffering from chronic fatigue syndrome due to chemotherapy treated with BioBran (MGN-3- Arabinoxylane) and targeted radiofrequency heat therapy PEER REVIEWED

  • Gabriel Petrovics, Gyula Szigeti, Szilárd Hamvas, Ágnes Máté, József Betlehem, Gabriella Hegyi*
  • (edited by Chris Gutch PhD.)
  • 2016

Introduction: Although modern therapies for cancer have improved life expectancy, the management of

disease and improvement of quality of life (QoL) of patients, especially managing cancer-related pain and

chronic fatigue syndrome are still limited. We demonstrate the efficacy of a combined therapy to treat cancer

patients suffering from CFS. The effects of a combined therapy in cancer patients suffering from CFS was

evaluated. NK cells were stimulated, additional tumour treatment together with targeted radiofrequency

therapy (Oncothermia).

Methods: SIXTY patients with CFS (due to suffering from any type of cancer) were recruited, (according to

the Centres for Disease Control 1994 criteria) attending an outpatient specialist CFS service for controlled

pilot study. A total of 25 participants were given oral BioBran (MGN-3-Arabinoxylane), + Oncothermia, for

six months, equivalent control group has not received this complex (BioBran + Oncothermia) treatment,

they received chemo-,radiotherapy treatment.

Results: The whole body pH status showed strong tissue acidity before the treatment, but the BioBran

group changed the tissue pH status. The most important finding was that the average of CFQ score was

significantly reduced after the treatment, and in control group the CFQ scores did not change


Conclusion: The findings support a specific therapeutic effect of the complex BioBran+ Oncothermia

therapy in CFS of cancer patients improving their QoL, enhancing NK activity in synergy.

© 2016 Published by Elsevier GmbH.

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