Biobran MGN-3 Academic Research

 

For a summary research overview by Dr. Maeda, please click here.

 
1989 A basic study of activation of host defence mechanism by food: paper by M. Yamazaki at the Faculty of Pharmaceutical Science at Teikyo University.
1992 Active hemicellulous compound (AHCC) enhance NK cell activity of aged mice in vivo: presentation by M. Ghoneum at the FASEB meeting in Anaheim, California. This compound was developed by H. Maeda as a precursor to MGN-3.
  Enhancement of human NK cell activity in vivo by AHCC: presentation by M. Ghoneum at the 7th Annual Conference on clinical Immunology in Philadelphia.
  Enhancement of NK cell activity in cancer patients by AHCC: presentation by M. Ghoneum at the Adjuvant Nutrition in Cancer Treatment conference in Tulsa Oklahoma.
1995 H. Maeda successfully develops commercially viable Biobran MGN-3 by using special extraction methods on rice bran at Daiwa Pharmaceutical in Japan. This proves much more potent than the AHCC he developed a few years earlier. Clinical trials with this new generation arabinoxylan compound begin.
  Immunomodulatory and anti-cancer properties of MGN-3, a modified xylose from rice bran, in 5 patients with breast cancer: presentation by M. Ghoneum of UCLA/Drew University at the American Association for Cancer Research at Baltimore, Maryland, USA. NK cell activity substantially increased within just a couple of weeks taking MGN-3 at a dose of 3g /day. Two patients who participated early in the study (6-8 months) went into complete remission. .
1996 NK immunomodulatory function in 27 cancer patients by MGN-3, a modified arabinoxylan from rice bran: presentation by M. Ghoneum at the 87th Annual Meeting of the American Association for Cancer research entitled. 7 patients had breast cancer, prostate; 8 multiple myeloma (MM); 3 leukemia and 2 cervical. All patients taking conventional treatments as well as 3g MGN-3 per day. All patients had significant rises in NK cell activity when taking MGN-3 (100 – 537% increases).
  Acute Oral Toxicity Test at the AMA Laboratories, New York, USA (Ref: WP96-BERN1/LD504881.DP) Animal Experiment involving rats to determine any potential toxicity of MGN-3. Above material can be classified as non-toxic according to the reference. LD50 > 36.0g / kg.
  Effect of MGN-3 on human natural killer cell activity and interferon-g synthesis in vitro: abstract of presentation given by M. Ghoneum at the ASBMB/ASIP/AAI joint meeting in New Orleans entitled. Conclusion was that MGN-3 is a potent Biological Response Modifier (BRM) as indicated by the significant increases in human NK cell activity at 16 hours post exposure through the production of IFN-G. MGN-3 also had direct anti-cancer activity in vitro.
  Anti-HIV activity by MGN-3 in vitro: abstract of presentation given by M. Ghoneum at the 11th International Conference on AIDS in Vancouver. Conclusion: MGN-3 possesses a potent effect against syncytia formation by HIV and may be of potential value in therapy for HIV infection.
1997 The effect of MGN-3, an arabinoxylan compound, on serum lipids in streptozotocin induced diabetic rats: abstract presented by Ohara, Tabuchi and Maeda (Japan) at the 38th Annual Meeting of The American College of Nutrition. MGN-3 was shown to reduce the rise in serum triglyceride and total cholesterol in diabetic rats indicating that it may be useful in the treatment of diabetes.
1998 Anti-HIV activity in vitro of MGN-3, an activated arabinoxylan from rice bran: paper by M. Ghoneum in the Biochemical and Biophysical Research Communications Journal 243, 25-29 (1998), Article No. RC978047. This is a detailed write up of the abstract Ghoneum presented in July 1996 at the International Conference on AIDS in Vancouver.
  Enhancement of human natural killer cell activity by modified arabinoxylan from rice bran (MGN-3): paper by M. Ghoneum in the International Journal of Immunotherapy XIV (2) 89-99 (1998). Study involved 24 individuals taking MGN-3 at 3 different concentrations. NK cell activity was significantly increased after 1 week and peaked at 2 months. Also measured was a significant increase in interferon-g.
  MGN-3 immunotherapy for the treatment of cancer: abstract presented by M. Ghoneum at the First International Symposium on Disease Prevention by IP6 and Other Rice Components in Japan. The 10 cancer patients in the study showed large increases in NK cell activity and elevated T and B cell function by its ability to produce cytokines such as TNF-a and IFN-g.
  Synergistic effect of modified arabinosylan (MGN-3) and low dose of recombinant IL-2 human NK cell activity and TNF-α production: presentation by M. Ghoneum and A. Jewett at the Conference of Anti-Aging Mechanism run by the American Academy of Anti-Aging Medicine in NJ.
  NK cell activity by MGN-3: presentation by M. Ghoneum at the 26th Academy of Alternative Medicine of Cancer in Los Angeles.
  Immunopotentiation by utilization of MGN-3 tissue: presentation by M. Ghoneum at the Congress on Anti-Aging Medicine in Nevada.
  NK immunorestoration of cancer patients by MGN-3, a modified arabinoxylan rice bran (study of 32 patients up to 4 years): paper by M. Ghoneum given at the 6th International Congress on Anti-Aging & Bio-Medical Technologies. Conclusion: MGN-3 is a potent biological response modifier in its ability to significantly increasing the activity of NK cells in both animals and humans. The mechanism by which it does this is firstly that it increases the granularity of the NK cells and secondly it elevates cytokine production.
  Active oxygen radical scavenging activity of the plant polysaccharide processed foodstuff Biobran: presentation by K. Tazawa, Toyama Medical and Pharmaceutical University, and H. Maeda, Daiwa Pharmaceutical Co. Ltd., at the 3rd JsoFF Conference.
1999 A case study of supplementary application of rice bran Arabinoxylan (MGN-3) to bone metastasis from lung cancer: presentation by T. Sobajima and H. Maeda at the 2nd Conference of Japanese Association for Alternative, Complementary and Traditional Medicine (JACT), Tokyo Japan. Sobajima T., Hoshigaoka Welfare Annuity Hospital and Maeda H., Daiwa Pharmaceutical Co. Ltd., Tokyo.
  Evaluation of MGN-3 (Biobran) on superoxide scavenging activity: presentation by K. Tazawa, H. Namikawa, S. Oida, K. Ito, M. Yatsuzuka, J. Koike, H. Maeda at the 6th Japanese Conference on Cancer Prevention, Tokyo Japan. Toyama Medical University.
  Modified rice bran improves glucose tolerance in NIDDM adult rats given streptozocin as neonates: presentation by Ohara I., Onai K. (Kobe Women's University) and Maeda H. (Daiwa) at the 40th meeting of the American College of Nutrition in Washington DC.
  Evaluation of MGN-3 (Biobran) with activation function of NK cell activity on superoxide scavenging activity: presentation by K. Tazawa, H. Namikawa, S. Oida, K. Ito, M. Yatsuzuka, J. Koike, M. Masada and H. Maeda at the 12th Japanese Conference on Bio Therapy, Yokohama Japan. Toyama Medical University, Chiba University and Daiwa Pharmaceutical.
  Application of modified rice bran dietary fiber to diabetes and taste preference in streptozotocin-included diabetic rats: presentation by I. Ohara, K. Onai and H. Maeda at the 2nd International Conference on Food Factors, Kyoto, Japan. Laboratory of Nutrition, Kobe Women's University, and Daiwa Pharmaceutical.
  Immunostimulation and Cancer Prevention: presentation by M. Ghoneum at the 7th International Congress on Anti-Aging & Biomedical Technologies, Las Vegas, USA. Drew University.
2000 Physiological Activator, Oryza Sativa L. Arabinoxylan Derivative (MGN-3): presentation by H. Maeda at the 6th Japanese Congress on Mibyo System, Hiroshima Japan. Daiwa Pharmaceutical Co. Ltd.
  Production of TNF-a and IFN-g From human peripheral blood lymphocytes by MGN-3, a modified arabinoxylan from rice bran: paper by Ghoneum and Jewett in Cancer Detection and Prevention, 24 (4): 314-324 (2000). This study showed that MGN-3 is a potent TNF-a producer and that it induces the TNF-a secretion in a dose dependent manner. Also, a combination of MGN-3 and IL-2 resulted in a synergistic induction of TNF-a and IFN-g secretion. MGN-3 appears to increase the expression of CD69 activation antigen.
  Effects of modified rice bran on serum lipids and taste preference in streptozotocin-induced diabetic rats: paper by Ohara, Agr, Tabuchi, Onai and Econ from Kobe Women's University in Kobe Japan in the Journal Of Nutritional Research, Vol. 20, No. 1, pp.59-68, 2000. The study was to determine whether the administration of MGN-3 could improve streptozotocin-induced diabetes. Results: serum triglycerides and total cholesterol decreased, and polyuria and taste was improved.
  The Effect of MGN-3 on cisplatin and adriamycin induced toxicity in the rat: paper by Jacoby, Wnorowski, Sakata and Maeda published in the American Society for Pharmacology and Experimental Therapeutics, Boston, USA. Conclusion: MGN-3 protects rates given an acutely toxic dose of cisplatin or adriamcyin. This indicates that the MGN-3 may well be good at improving the quality of life in patients receiving chemotherapy and may be a useful adjunct, therefore, to cancer chemotherapy. Product Safety Lab. and Daiwa Pharmaceutical Co. Ltd.
  Inhibitory effects of MGN-3 (modified Arabinoxylan from rice bran) on free radical: presentation by T. Saito, H. Ohkami, K. Tsukada, K. Tazawa, H. Namikawa, S. Oida, J. Koike, M. Yatsuzuka, M. Masada, and H. Maeda at the 59th Annual Meeting of the Japanese Cancer Association, Yokohama Japan. Toyama Medical University, Chiba University and Daiwa Pharmaceutical.
  Evaluation of immune (arabinoxylan) therapy seen from NK cell activity and the CD4/CD8 ration on cancer patients: The 3rd Annual Meeting of the Japanese Society for Complementary & Alternative Medicine & Treatment, Tokyo, Japan.
  Natural biological response modifier (MGN-3) shown to be effective against tumor cell growth: presentation by M. Ghoneum, K. Tachiki, K. Ueyama, T. Makinodan, N. Makhijani and D. Yamaguchi at the 8th International Congress on Anti-Aging & Biomedical Technologies, December 14-17, 2000, Las Vegas, NV.
2001 Application of the alterantive medicine of a new physiological active substance "arabinoxylan derivative" (MGN-3, Biobran): 7th Conference of Japan Mibyou System Association, Nagoya, Japan. Maeda H., Daiwa Pharmaceutical Co. Ltd.
  MGN-3, a novel antitumor agent: presentation by K. Uyemura, K. Tachiki, M. Ghoneum, T. Makinodan, N. Makhijani and D. Yamaguchi at the 92nd Annual Meeting, American Association for Cancer Research. The research team found that MGN-3 not only increased NK cell activity, but also the production and secretion of cytokines such as IL-10 and IL-12 by cancer cells such as MCF-7. Treatment of cultures of MCF-7 cells with MGN-3 also can arrest cell growth.
  Inhibitory effect of MGN-3 on the progress of atopic dermatitis in NC mice: presentation by S. Nonoyama and L. Lin at 11th International Congress of Immunology and written up in the Scandinavian Journal of Immunology — Volume 54, Supplement 1, July / August 2001.
  A Descriptive Questionnaire-Based Study on the Use of Biobran (MGN-3) in Chronic Fatigue Syndrome: study by Dr. J. Kenyon published in the Townsend Letter, November 2001.
2002 Study on the growth inhibiting component of cancerous cells in culture cell lines derived from modified rice-bran arabinoxylan: paper presented at the 46th Japan Society for Bioscience, Biotechnology and Agrochemistry by Miyazaki F., Hashizume T., Kodama H., Maeda H. and M. Masada. Technology Department, Kazami Co., Ltd.,Department of Biresources Chemistry, Faculty of Horticulautre, Chiba University and Daiwa Pharmaceutical Co., Ltd.
  Effects of modified rice-bran arabinoxylan on NK activity of human peripheral blood lymphocytes: paper presented at the 46th Japan Society for Bioscience, Biotechnology and Agrochemistry, Sendai, Japan by Shimomura C., Ueda Y., Kodama H., Maeda H. and M. Masada, Department of Bioresources Chemistry, Faculty of Horticulture, Chiba University and Daiwa Pharmaceutical Co., Ltd.
  Effects of rice bran arabinoxylan on induced hepatitis in rats (in Japanese): paper by Maeda H. et al. published in the Journal of Japanese Association for Dietary Fiber Research (Vol 6, No 2)
  Normalization of the lymphocyte system in peripheric blood reaction by arabinoxylan from rice bran (MGN-3): paper presented at the 43rd Annual Meeting at the American Clooege of Nutrition, San Antonio, Texas, by Ueda Y., Masada M. and H. Maeda. Department of Bioresources Chemistry, Faculty of Horticulature, Chiba University and Daiwa Pharmaceutical Co. Ltd.
  MGN-3 potentiates death receptor-induced apoptosis in cancer cells: paper presented at the 93rd Annual Meeting 2003 of American Association for Cancer Research, Boston, USA by M. Ghoneum and S. Gollapudi, Drew University of Medicine and Science, Los Angeles, CA, UC Irvine, Division of Basic and Clinical Immunology, Irvine CA.
  A basic study on protective effects of Biobran against myelogenetic death by radiation exposure: paper by Dr. S. Nakatugawa of Nagoya University Medical School Hospital in Japan given at the American Association for Cancer Research meeting in Boston, MA.
  Modified rice bran beneficial for adverse effect of cisplatin to prevent weigth loss of mice: paper by Yuzo Endo and Hiroshi Kanbayashi from McMaster University in Ontario Canada given at the American Association for Cancer Research meeting in Boston, MA (also published in Pharmacology and Toxicology).
  Effect of enzyme-processed rice bran hemicellulose (MGN-3) on experimental liver dysfunction in rats: paper presented at the 7th Conference of Japanese Association for Dietary Fiber Research, Tokyo, Japan by Yamada T., Daizou A., Poindoglun K., Egashira K., Maeda H. and Sanada H. Graduate School of Science and Technology, Chiba University, Department of Bioresources Chemistry, Chiba University and Daiwa Pharmaceutical Co. Ltd.
  Significant of sthmatic mouse model exposed to antigen (Toluene Diisocyanate) for a prolonged period: paper presented at the 52nd Conference of Japanese Society of Allergology, Yokohama, Japan by Kanbayshi H. and Y. Endo, Department of Pathological Molecular Medicine, McMaster University.
  Evaluation of the effects of asthma prevention and symptom reduction by enzymatically modified rice-bran foods in asthmatic model mice: paper presented at the 52nd Conference of Japanese Society of Allergology, Jokohama, Japan by Kanbayashi H. and Endo Y., Department of Pathological Molecular Medicine, McMaster University.
2003 Effect of Biobran proved by Scientific Studies: Japanese Academy for Clinical Complementary & Alternative Medicine, Maeda H., Daiwa Pharmaceutical Co. Ltd.
  A novel approach to breast cancer therapy: modified arabinoxylan rice bran (MGN-3/Biobran) enhances apoptosis of human breast cancer cells following phagocytosis of saccharomyces cerevisiae, the baker's yest, in vitro: presentation by Ghoneum M. (UCLA) and Gollapudi S. (University of California Irvine) at The Japanese Society for Complementary and Alternative Medicine, Sendai American Association for Cancer Research Speicial Conference in California.
  Immunoactivation therapy for various prograssive cancers using rice bran arabinoxylan derivative (Biobran): The Japanese Society for Complementary and Alternative Medicine, Tsunekawa H. and Maeda H.
  Modified arabinoxylan rice bran (MGN-3 /Biobran) sensitizes human T cell leukemia cells to death receptor (CD95)-induced apoptosis: paper by Mamdooh Ghoneum and Sastry Gollapudi published in Cancer Letters 201 (2003) 41-49 / Elsevier.
  The oral administration of the hydrolysis rice bran prevents a common cold syndrom for elderly perople based on immunomodulatory function: Medical and Pharmaceutical Society for Wakan Yaku, Maeda H., Omura K. and Zhu K., Daiwa Pharmaceutical Co. Ltd.
  The effect in the physiological function of a modified arabinoxylan rice bran: Japan Society for Biological Therapy, Masada M., Maeda H. and Tazawa K., Chiba University, Daiwa Pharmaceutical Co. Ltd., Toyama Medical University.
  Effect of rice bran arabinosylan and shark lipid extract on complementary and alternative therapy: paper presented by Omori T. (Ginza San Espero Omori Clinic) at the 7th Conference of the Japanese Assoc. for Alternative, Complementary and Traditional Medicine (JACT) at Kobe.
2004 Modified arabinoxylan rice bran (MGN-3 /Biobran) potentiates apoptosis in cancer cells induced by multiple anti-cancer agents in vitro: paper presented by Ghoneum M. and Gollapudi S. at the 7th International Symposium on Predictive Oncology & intervention Strategies in Nice.
  The Clinical Significance of Biobran in the Immunotherapy for Cancer: paper by Yasushi Okamura, Director of the Insitute of Life Science, Japan, published in Clinical Pharmacology and Therapy Vol. 14/No.3
  One Case of a Patient with Umbilical Metastasis of Recurrental Cancer (Sister Mary Joseph's Nodule, SMJN) Who has Survived for a Long Time under Immunomodulatory Supplement Therapy: paper by Tomonori Kawai, Shinkurashiki icho komon geka, published in Clinical Pharmacology and Therapy Vol. 14/No.3
  The Life Prolongation and QOL Improvement Effect of Rice Bran Arabinoxylan Derivative (MGN-3, Biobran) for Progressive Cancer: paper by Kihachiro Takahara and Kamataro Sano, Sano Surgery Clinic, published in Clinical Pharmacology and Therapy Vol. 14/No.3
  Effect of Long-term Administration of Immunomodulatory Food on Cancer Patients Completing Conventional Treatments: paper by Hiroshi Tsunekawa, Tsunekawa Gastrointestinal Clinic, published in Clinical Pharmacology and Therapy Vol. 14/No.3
  A Case Where an Immunomodulatory Food was Effective in Conservative Therapy for Progressive Terminal Pancreatic Cancer: paper by Kazutoshi Kaketani, Hanzomon Gastrointestinal Clinic, published in Clinical Pharmacology and Therapy Vol. 14/No.3
  Effect of the oral administration of hydrolyzed rice bran (HRB) on the common cold syndrome of the elderly: paper presented by Omura K. (Dokkyo University School of Medicine), Ichihashi K. (Ichihashi Clinic), Maeda H. (Daiwa Pharmaceutical) and Tazawa K. (Toyama Medical and Pharmaceutical University) at the 4th Conference of the Japanese Society of Anti-Aging Medicine in Tokyo.
  Repeat presentation of the above paper at the 21st Symposium of Medical and Pharmaceutical Society for Wakan-Yaku.
  Evaluation of the effect of hyrolyzed rice bran on reducing respiratory symptoms in smokers: paper by Kudo M., Maeda H. (Daiwa) and Nakamichi N. (Jikei University, N.S. Clinic) at the 21st Symposium of Medical and Pharmaceutical Society for Wakan-Yaku.
  Chemical structure of immunostimulating substances from rice bran: paper presented by Miura T., Chiba M., Miyazaki Y., Kato Y. (Hirosaki University) and Maeda H. (Daiwa Pharmaceutical) at the 2004 Annual Meeting of the Japanese Society of Applied Glycoscience and the 12th Symposium on Amylases and Related Enzymes, Kagoshima.
  Hyrolyzed rice bran reduces the aggravation of protein metabolism in streptozotocin-induced diabetic rats: paper by Kitamura N., Ohara I., (Aichi Gakusen University) and Maeda H. (Daiwa Pharmaceutical) at the 45th Annual Meeting of the American College of Nutrition in California.
  Enhancement of natural killer cell activity of aged mice by modified arabinoxylan rice bran (MGN-3 /Biobran): paper by M. Ghoneum and S. Abedi in the Journal of Pharmacy and Pharmacology (56: 1581-1588).
  Induction of apoptosis in breat cancer cells by Saccharomyces Cerevisiae, the Baker's Yeast, in vitro: paper by M. Ghoneum and S. Gollapudi in Anticancer Research vol 24: 1455-1464.
2005 Modified Arabinoxylan Rice Bran (MGN-3/Biobran) Enhances Yeast-induced Apoptosis in Human Breast Cancer Cells In Vitro: paper by M. Ghoneum and S. Gollapudi in Anticancer Research vol 25: 859-870
  Human Squamous Cell Carcinoma of the Tongue and Colon Undergoes Apoptosis upon Phagocytosis of Saccharomyces Cerevisiae, the Baker's Yeast, In Vitro: paper by M. Ghoneum, J. Hamilton, J. Brown, S. Gollapudi in Anticancer Research vol 25: 981-990
  Synergistic Role of Arabinoxylan Rice Bran (MGN-3/Biobran) in S. cerevisiae-induced Apoptosis of Monolayer Breast Cancer MCF-7 Cells: paper by M. Ghoneum and S. Gollapudi in Anticancer Research vol25: 4187-4196
  A case where immunomodularity food and anti-oxidant therapy ws effective in a case of advanced prostate cancer: report by Dr. Serge Jurasunas of the Holiterapias Institute in Portugal.
2006 Metastatic Hemangiopericytoma of the Skin Treated with Wide Local Excision and MGN-3: paper by J Markus, A. Miller, M. Smith, I. Orengo in Dermatological Surgery 32:1:January
  Apoptosis of Breast Cancer MCF-7 Cells In Vitro is Induced Specifically by Yeast and Not by Fungal Mycelia: paper by M. Ghoneum and S. Gollapudi in Anticancer Research 26: 2013-2022
2007 Yeast Therapy For the Treatment of Cancer and its Enhancement by MGN-3/Biobran, an Arabinoxylan Rice Bran: paper by M. Ghoneum, J. Brown and S. Gollapudi in Cellular Signaling and Apoptosis Research pp 185-200 / Chapter VI
2008 In Vivo Tumor Inhibitory Effects of Nutritional Rice Bran Supplement MGN-3/Biobran on Ehrlich Carcinoma-Bearing Mice: paper by N. El-Din, E. Noaman and M. Ghoneum in Nutrition and Cancer, 60(2), 235-244
  MNG-3/Biobran, modified arabinoxylan from rice bran, sensitizes human breast cancer cells to chemotherpeutic agent, daunorubicin: paper by S. Gollapudi and M. Ghoneum in Cancer Detection and Prevention 32(2008) 1-6
  Modified Arabinoxylan Rice Bran (MGN-3/Biobran) Enhances Intracellular Killing of Microbes by Human Phagocytic Cells In Vitro: paper by M. Ghoneum, M. Matsuura and S. Gollapudi in the International Journal of Immunopathology and Pharmacology Vol. 21, no. 1, 87-95
  Synergistic Role of Arabinoxylan Rice Bran (MGN-3/Biobran) in S. cerevisiae-induced Apoptosis of Monolayer Breast Cancer MCF-7 Cells: Authors: M. Ghoneum and S. Gollapudi published in Anticancer Research 25: 4187-4196.
  MGN-3/Biobran, modified arabinoxylan from rice bran, sensitizes human breast cancer cells to chemotherapeutic agent, daunorubicin: Authors: S. Gollapudi and M. Ghoneum published in Cancer Detection and Prevention 32 (2008) 1-6.
  Modulation of the anticancer immunity by natural agents: inhibition of T regulatory lymphocyte generation by arabinoxylan in patients with locally limited or metastatic solid tumors: Authors: P. Lissoni, G. Messina, F. Brivio, L. Fumagalli, L. Vigore, F. Rovelli, L. Maruelli, M. Miceli, P. Marchiori, G. Porro, M. Held, G. di Fede, T Uchiyamada, published in Cancer Therapy Vol 6, 1011-1016.
 

Comparative study of four flourescent probes for evaluation of natural killer cell cytotoxicity assays: Authors: Cholujova, Jakubikova, Kubes, Arendacka, Sapak, Robert, Sedlak published in Immunobiology - 2008; 213(8):629-40.

2009 Biobran-augmented maturation of human monocyte derived dendritic cells: Authors: D. Cholujova, J. Jakugikova, J. Sedlak published in Neoplasma 56, 2, 2009.
2010 Arabinoxylan Rice Bran (MGN-3) Enhances the Effects of Interventional Therapies for the Treatment of Hepatocellular Carcinoma: A Three-year Randomized Clinical Trial. Authors Mai Hong Bang, Tran Van Piep, Nguyen Tien Thinh, Le Huu Song, Trinh Tuan Dung, Le Van Truong, Le Van Don, Thai Doan Ky, Deyu Pan, Magda Shaheen and Mamdooh Ghoneum published in Anticancer Research 30: 5145-5152 (2010).
 
 

For more detailed research, including case studies, visit:

 
www.jafra.gr.jp…   Japanese site, in English, dedicated to research information on MGN-3 arabinoxylan compound as well as other functional foods.
     
www.dhdeurope.sk…   DHD Europe is the European branch of Daiwa Pharmaceutical and their site contains many scanned copies of the research papers listed above.
     
www.daiwa-pharm.com   Latest news on research, papers, conferences and other activity from the manufacturers in Japan.
     
     
 
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  Biobran and MGN-3 are both registered trademarks of Daiwa Pharmaceutical, Tokyo, Japan
MGN-3 is also the generic/research name for Daiwa Pharmaceutical's arabinoxylan complex